2021

• Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope.

  Sci Rep 11, 1278 (2021) doi: 10.1038/s41598-020-80156-w

• Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)

  ACS Chem. Neurosci. 2021, 12, 1, 203–215, (2021) doi: 10.1021/acschemneuro.0c00687

• All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species.

  Proceedings of the National Academy of Sciences Sep 2021, 118 (36) e2105548118, (2021) doi: 10.1073/pnas.2105548118

• MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDL receptor Missense Variants

  Atherosclerosis 331 (2021) e3, (2021) doi: 10.1016/j.atherosclerosis.2021.06.013

• Minimal metabolism: a key concept to investigate the origins and nature of biological systems.

  BioEssays, 43, e2100103, (2021) doi: 10.1002/bies.202100103

• A Systematic Approach to Assess the Activity and Classification of PCSK9 Variants.

  Int. J. Mol. Sci. 2021, 22(24), 13602; (2021) doi: 10.3390/ijms222413602

• Magnesium accumulation upon cyclin M4 silencing activates microsomal triglyceride transfer protein improving NASH

  J. Hepatol. 2021, 75, 34–45, (2021) doi: 10.1016/j.jhep.2021.01.043

• Reliably quantifying the evolving worldwide dynamic state of the COVID-19 outbreak from death records, clinical parametrization, and demographic data.

  Sci Rep 11, 19952 (2021) doi:10.1038/s41598-021-99273-1

• BioMetAll: Identifying Metal-Binding Sites in Proteins from Backbone Preorganization.

  J. Chem. Inf. Model. 2021, 61, 1, 311–323, (2021) doi: 10.1021/acs.jcim.0c00827

• Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach.

  Cancers 2021, 13(12), 2936; (2021) doi: 10.3390/cancers13122936

• Lipoprotein(a) in heterozygous familial hypercholesterolemia. Influence of the causative gene and type of mutation.

  Atherosclerosis, Available online 23 August 2021 In Press, Corrected Proof (2021) doi: 10.1016/j.atherosclerosis.2021.08.009

• Laboratory Detection of Cyanoacetic Acid: A Jet-cooled Rotational Study.

  The Astrophysical Journal, 915:76 (8pp), (2021) doi: 10.3847/1538-4357/ac013f

• Measuring In-Vivo Protein Turnover and Exchange in Macromolecular Assemblies

  STAR Protocols 2, 100800, September 17, 2021 (2021) doi: 10.1016/j.xpro.2021.100800

• Shape of Testosterone.

  J. Phys. Chem. Lett. 2021, 12, 29, 6983–6987, (2021) doi: 10.1021/acs.jpclett.1c01743

• Aberrant Synaptic PTEN in Symptomatic Alzheimer’s Patients May Link Synaptic Depression to Network Failure

  Front. Synaptic Neurosci. 13:683290, (2021) doi: 10.3389/fnsyn.2021.683290

• Degradation of Drug Delivery Nanocarriers and Payload Release: A Review of Physical Methods for Tracing Nanocarrier Biological Fate.

  Pharmaceutics 2021, 13(6), 770; (2021) doi: 10.3390/pharmaceutics13060770

• LDLR variants functional characterization: contribution for variant classification

  Atherosclerosis 329 (2021) 14–21, (2021) doi: 10.1016/j.atherosclerosis.2021.06.001

• Tissue mechanics in morphogenesis: Active control of tissue material properties to shape living organisms

  Cells & Development, 203777 (2021) https://doi.org/10.1016/j.cdev.2022.203777

• Ascertaining the initiation of epidemic resurgences: an application to the COVID-19 second surges in Europe and the Northeast United States.

  R. Soc. open sci., 8: 210773, (2021) doi:1 0.1098/rsos.210773

• Editorial: ‘Inter-identities' in Life, Mind, and Society.

  Front. Psychol. 12:704772, (2021) doi: 10.3389/fpsyg.2021.704772

• The role of the intramolecular interactions in the structural behavior of biomolecules: Insights from rotational spectroscopy

  Developments in Physical & Theoretical Chemistry, Intra- and Intermolecular Interactions Between Non-covalently Bonded Species, 2021, 93-141, (2021) doi: 10.1016/B978-0-12-817586-6.00004-9

• Mitochondrial bioenergetics boost macrophage activation, promoting liver regeneration in metabolically compromised animals

  Hepatology (2021), Volume 75, Issue 3 p. 550-566, doi.org/10.1002/hep.32149

• Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease.

  Sci Rep 11, 23315 (2021) doi: 10.1038/s41598-021-02432-7

• Laboratory Observation of, Astrochemical Search for, and Structure of Elusive Erythrulose in the Interstellar Medium

  J. Phys. Chem. Lett. 2021, 12, 4, 1352–1359, (2021) doi: 10.1021/acs.jpclett.0c03050

• Mitochondrial bioenergetics boost macrophages activation promoting liver regeneration in metabolically compromised animals.

  Hepatology. 00: 1– 17 (2021) doi:10.1002/hep.32149

• Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells.

  Pharmaceutics 2021, 13(5), 696; (2021) doi: 10.3390/pharmaceutics13050696

• Molecular docking, SAR analysis and biophysical approaches in the study of the antibacterial activity of ceramides isolated from Cissus incisa

  Bioorganic Chemistry 109 (2021) 104745, (2021) doi: 10.1016/j.bioorg.2021.104745

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).

  Autophagy, 17:1, 1-382, (2021) doiI: 10.1080/15548627.2020.1797280

• Associative conditioning is a robust systemic behaviour in unicellular organisms: an interspecies comparison.

  Front. Microbiol. 12:707086, (2021) doi: 10.3389/fmicb.2021.707086

• Use of pore-forming toxins to study co-translocational protein folding

  Methods in Enzymology, 649, 2021, 635-649, (2021 )doi: 10.1016/bs.mie.2021.01.018

• The role of the intramolecular interactions in the structural behavior of biomolecules: Insights from rotational spectroscopy

  Developments in Physical & Theoretical Chemistry, Pages 93-141 (2021) doi: 10.1016/B978-0-12-817586-6.00004-9. (2021)

• Oligonucleotide-Directed Protein Threading Through a Rigid Nanopore.

  Nanopore Technology. Methods in Molecular Biology, vol 2186. Humana, New York, NY, (2021) doi: 10.1007/978-1-0716-0806-7_10

• Fluorine Labeling of Nanoparticles and In Vivo 19F Magnetic Resonance Imaging

  ACS Appl. Mater. Interfaces 2021, 13, 11, 12941–12949, (2021) doi: 10.1021/acsami.1c01291

• The Role of Non‑Covalent Interactions on Oligomer Formation: Pentamer, Hexamers and Heptamer of Difluoromethane.

  Angew. Chem. Int. Ed., 60, 16894, (2021) doi: 10.1002/anie.202103900

• SR-B1, a key receptor involved in the progression of cardiovascular disease: a perspective from mice and human genetic studies.

  Biomedicines 2021, 9(6), 612; (2021) doi: 10.3390/biomedicines9060612

• Single-molecule conformational dynamics of viroporin ion channels regulated by lipid-protein interactions

  Bioelectrochemistry 137 (2021) 107641, (2021) doi: 10.1016/j.bioelechem.2020.107641

• An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel.

  BMC Biol 19, 109 (2021) doi: 10.1186/s12915-021-01040-1

• Transcription-mediated supercoiling regulates genome folding and loop formation.

  Molecular Cell 81, 3065–3081, (2021) doi: 10.1016/j.molcel.2021.06.009

• Antibodies response induced by recombinant virus-like particles from Triatoma virus and chimeric antigens from Trypanosoma cruzi

  Vaccine 39 (2021) 4723–4732, (2021) doi: 10.1016/j.vaccine.2021.05.039.

• The interaction of Aβ42 peptide in monomer, oligomer or fibril forms with sphingomyelin/cholesterol/ganglioside bilayers

  Int J Biol Macromol. S0141-8130(20)35037-6. doi: 10.1016/j.ijbiomac.2020.11.112. (2021)