Mechanisms of Celullar Membrane Remodelling Laboratory

It all began some 2 billion years ago, when endosymbiosis changed forever the internal world of eukaryotic cells. The sudden engulfment of bacteria, allowed the eukaryotic cells to have an alternative source of energy, but another important evolution step took place through the symbiosis. This mostly overlooked event was the birth of a new protein family, called dynamins, that took control over the dynamics of the endomembrane systems in Eukaryotes. We want to understand how the evolution of dynamins correlates with that of endomembrane systems.