Publications
2021
Super-Resolution Microscopy Using a Bioorthogonal-Based Cholesterol Probe Provides Unprecedented Capabilities for Imaging Nanoscale Lipid Heterogeneity in Living Cells.
Small Methods, 5, 2100430, (2021) doi: 10.1002/smtd.202100430
Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-based Disaggregase.
Int. J. Mol. Sci. 2021, 22(23), 12983; (2021) doi: 10.3390/ijms222312983
Molecular mechanisms of lipotoxicity-induced pancreatic β-cell dysfunction
International Review of Cell and Molecular Biology, Academic Press, Volume 359, 2021, 357-402, (2021) doi: 10.1016/bs.ircmb.2021.02.013
Phase-selective staining of model and cell membranes, lipid droplets and lipoproteins with fluorescent solvatochromic pyrene probes
Biochim Biophys Acta Biomembr. 1863(1):183470. (2021) doi: 10.1016/j.bbamem.2020.183470. (2021)
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Nat Commun 12, 3661 (2021) doi: 10.1038/s41467-021-23825-2
Rotational spectroscopic study and astronomical search for propiolamide in Sgr B2(N).
A&A 647, A55 (2021) doi: 10.1051/0004-6361/202040211
Nonlinear material and ionic transport through membrane nanotubes
BBA - Biomembranes 1863 (2021) 183677, (2021) doi: 10.1016/j.bbamem.2021.183677
2020
A Compression Engine to Coordinate Tissue Elongation in the Embryo
Dev Cell. 55(3):256-258. (2020) doi: 10.1016/j.devcel.2020.10.013. (2020)
Commercial and farm fermented liquid organic amendments to improve soil quality and lettuce yield
J Environ Manage. 264:110422. (2020) doi: 10.1016/j.jenvman.2020.110422 (2020)
Atomistic Insights of Calmodulin Gating of Complete Ion Channels
Int J Mol Sci. 21(4). pii: E1285. (2020) doi: 10.3390/ijms21041285. (2020)
Pathophysiology of Type 2 Diabetes Mellitus
Int J Mol Sci. 21(17):E6275. (2020) doi: 10.3390/ijms21176275. (2020)
Substrate-Enzyme Interactions in Intramembrane Proteolysis: ?-Secretase as the Prototype
Front Mol Neurosci. 13:65 (2020). doi: 10.3389/fnmol.2020.00065 (2020)
Sphingolipids in Non-Alcoholic Fatty Liver Disease and Hepatocellular Carcinoma: Ceramide Turnover
Int J Mol Sci. 21(1):40. doi: 10.3390/ijms21010040. (2020)
Cholesterol in the Viral Membrane is a Molecular Switch Governing HIV-1 Env Clustering
Advanced Science. 2003468. (2020) doi: 10.1002/advs.202003468 (2020)
Plasma lipids are associated with white matter microstructural changes and axonal degeneration
Brain Imaging Behav. (2020). doi: 10.1007/s11682-020-00311-9. Online ahead of print. (2020)
Free-energy landscapes of membrane co-translocational protein unfolding
Commun Biol. 3(1):160. (2020) doi: 10.1038/s42003-020-0841-4. (2020)
Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town
Arterioscler Thromb Vasc Biol. ATVBAHA120314482. (2020) doi: 10.1161/ATVBAHA.120.314482. Online ahead of print. (2020)
Definitions of life as epistemic tools that reflect and foster the advance of biological knowledge
Synthese. (2020) doi: 10.1007/s11229-020-02736-7. (2020)
Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR
Scientific reports, 10 (1), 1727. (2020) DOI: 10.1038/s41598-020-58734-9 (2020)
High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment.
Cancer Res. 80(19):4244-4257. (2020) doi: 10.1158/0008-5472.CAN-20-1117. (2020)
Irreversible versus repairable membrane poration: differences in permeabilization elicited by Bordetella Adenylate Cyclase Toxin and its hemolysin domain in macrophages
FEBS J. Article in press. doi: 10.1111/febs.15106. (2020)
BIRC6 Is Associated with Vulnerability of Carotid Atherosclerotic Plaque
Int J Mol Sci. 21(24):E9387. (2020) doi: 10.3390/ijms21249387. (2020)
Presenilin1 familial Alzheimer disease mutants inactivate EFNB1- and BDNF-dependent neuroprotection against excitotoxicity by affecting neuroprotective complexes of N-methyl-d-aspartate receptor
Brain Commun. 2(2):fcaa100. (2020) doi: 10.1093/braincomms/fcaa100. (2020)
MCDCalc: Markov Chain Molecular Descriptors Calculator for Medicinal Chemistry
Curr Top Med Chem. 20(4):305-317. (2020) doi: 10.2174/1568026620666191226092431. (2020)
Exploring polar headgroup interactions between sphingomyelin and ceramide with infrared spectroscopy
Sci Rep. 10(1):17606. (2020) doi: 10.1038/s41598-020-74781-8. (2020)
Predicting coated-nanoparticle drug release systems with perturbation-theory machine learning (PTML) models
Nanoscale. (25):13471-13483 (2020). doi: 10.1039/d0nr01849j. (2020)
Correction: Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities
J Biol Chem. 295(5):1368. (2020) doi: 10.1074/jbc.AAC120.012555 (2020)
Nucleophosmin, a multifunctional nucleolar organizer with a role in DNA repair
Biochim Biophys Acta Proteins Proteom. 1868(12):140532. (2020) doi: 10.1016/j.bbapap.2020.140532. (2020)
Tandem NMR and mass spectrometry analysis of human nuclear membrane lipids
Anal Chem. 92(10):6858-6868. (2020) doi: 10.1021/acs.analchem.9b05052 (2020)
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors
Cell Death Dis. 11(12):1039. (2020) doi: 10.1038/s41419-020-03256-5. (2020)
Dissecting the Structural and Chemical Determinants of the \\
Biochemistry. 59(32):2934-2945. (2020) doi: 10.1021/acs.biochem.0c00376 (2020)
Conformational impact of aliphatic side chains in local anaesthetics: benzocaine, butamben and isobutamben
Chem Commun (Camb). 56(45):6094-6097. (2020) doi: 10.1039/d0cc00760a. (2020)
Perturbation-Theory Machine Learning (PTML) Multilabel Model of the ChEMBL Dataset of Preclinical Assays for Antisarcoma Compounds
ACS Omega. 5(42):27211-27220. (2020) doi: 10.1021/acsomega.0c03356. (2020)
Chlorination and tautomerism: a computational and UPS/XPS study of 2-hydroxypyridine ? 2-pyridone equilibrium
Phys Chem Chem Phys. 22(24):13440-13455 (2020). doi: 10.1039/d0cp02304c. (2020)
Recent Developments in the Design of Non-Biofouling Coatings for Nanoparticles and Surfaces
Int. J. Mol. Sci. 21(3), 1007 (2020). https://doi.org/10.3390/ijms21031007. (2020)
C24:0 and C24:1 sphingolipids in cholesterol-containing, five- and six-component lipid membranes
Sci Rep. 10(1):14085. (2020) doi: 10.1038/s41598-020-71008-8. (2020)
A rotational study of the AlaAla dipeptide
Phys Chem Chem Phys. 22(25):13867-13871 (2020). doi: 10.1039/d0cp01043j. (2020)
Boundary versus enabling conditions for the origins of life: Comment on \\
Phys Life Rev. 34-35:96-98. (2020) doi: 10.1016/j.plrev.2020.06.001 (2020)
Diagnostic yield of sequencing familial hypercholesterolemia genes in individuals with primary hypercholesterolemia
Rev Esp Cardiol (Engl Ed). 2020 Jul 10:S1885-5857(20)30252-8. doi: 10.1016/j.rec.2020.06.003. Online ahead of print. (2020)
Nucleophosmin interaction with APE1: Insights into DNA repair regulation
DNA Repair (Amst) 88:102809. (2020) doi: 10.1016/j.dnarep.2020.102809 (2020)