Publications
2021
CHO/LY-B cell growth under limiting sphingolipid supply: Correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes.
The FASEB Journal, 35:e21657 (2021) doi: 10.1096/fj.202001879RR
Prediction of Anti-Glioblastoma Drug-Decorated Nanoparticle Delivery Systems Using Molecular Descriptors and Machine Learning.
Int. J. Mol. Sci. 2021, 22(21), 11519; (2021) doi: 10.3390/ijms222111519
Immunogenomics of Colorectal Cancer Response to Checkpoint Blockade: Analysis of the KEYNOTE 177 Trial and Validation Cohorts
Gastroenterology 2021;161:1179–1193, (2021) doi: 10.1053/j.gastro.2021.06.064
Conformational plasticity underlies membrane fusion induced by an HIV sequence juxtaposed to the lipid envelope.
Sci Rep 11, 1278 (2021) doi: 10.1038/s41598-020-80156-w
Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML)
ACS Chem. Neurosci. 2021, 12, 1, 203–215, (2021) doi: 10.1021/acschemneuro.0c00687
All-or-none amyloid disassembly via chaperone-triggered fibril unzipping favors clearance of α-synuclein toxic species.
Proceedings of the National Academy of Sciences Sep 2021, 118 (36) e2105548118, (2021) doi: 10.1073/pnas.2105548118
MLb-LDLr: A Machine Learning Model for Predicting the Pathogenicity of LDL receptor Missense Variants
Atherosclerosis 331 (2021) e3, (2021) doi: 10.1016/j.atherosclerosis.2021.06.013
2020
C24:0 and C24:1 sphingolipids in cholesterol-containing, five- and six-component lipid membranes
Sci Rep. 10(1):14085. (2020) doi: 10.1038/s41598-020-71008-8. (2020)
A rotational study of the AlaAla dipeptide
Phys Chem Chem Phys. 22(25):13867-13871 (2020). doi: 10.1039/d0cp01043j. (2020)
Boundary versus enabling conditions for the origins of life: Comment on \\
Phys Life Rev. 34-35:96-98. (2020) doi: 10.1016/j.plrev.2020.06.001 (2020)
Diagnostic yield of sequencing familial hypercholesterolemia genes in individuals with primary hypercholesterolemia
Rev Esp Cardiol (Engl Ed). 2020 Jul 10:S1885-5857(20)30252-8. doi: 10.1016/j.rec.2020.06.003. Online ahead of print. (2020)
Nucleophosmin interaction with APE1: Insights into DNA repair regulation
DNA Repair (Amst) 88:102809. (2020) doi: 10.1016/j.dnarep.2020.102809 (2020)
Structural characterization of the ICOS/ICOS-L immune complex reveals high molecular mimicry by therapeutic antibodies
Nat Commun. 11(1):5066. (2020) doi: 10.1038/s41467-020-18828-4. (2020)
The Construction of Biological \'Inter-Identity\' as the Outcome of a Complex Process of Protocell Development in Prebiotic Evolution
Front Physiol. 11:530 (2020). doi: 10.3389/fphys.2020.00530 (2020)
Photoacoustic effect applied on model membranes and living cells: direct observation with multiphoton excitation microscopy and long-term viability analysis
Sci Rep. 10(1):299. (2020) doi: 10.1038/s41598-019-56799-9. (2020)
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Nat Commun. 11(1):4033. (2020) doi: 10.1038/s41467-020-17473-1. (2020)
Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin
Nat Commun. 11(1):1916 (2020) doi: 10.1038/s41467-020-15698-8 (2020)
?-Amyloid (1-42) peptide adsorbs but does not insert into ganglioside-containing phospholipid membranes in the liquid-disordered state: modelling and experimental studies
Int J Biol Macromol. 164:2651-2658. (2020) doi: 10.1016/j.ijbiomac.2020.08.165. (2020)
Statin Treatment-Induced Development of Type 2 Diabetes: From Clinical Evidence to Mechanistic Insights
Int J Mol Sci. 21(13):4725. (2020) doi: 10.3390/ijms21134725. (2020)
Fluorescence Microscopy of the HIV-1 Envelope
Viruses 12(3), 348. (2020) https://doi.org/10.3390/v12030348 (2020)
High-speed atomic force microscopy highlights new molecular mechanism of daptomycin action
Nat Commun. 2020 Dec 9;11(1):6312. doi: 10.1038/s41467-020-19710-z. PMID: 33298927
Cholesterol Efflux Efficiency of Reconstituted HDL Is Affected by Nanoparticle Lipid Composition
Biomedicines. 8(10):E373. (2020) doi: 10.3390/biomedicines8100373 (2020)
PTML Model for Selection of Nanoparticles, Anticancer Drugs, and Vitamins in the Design of Drug-Vitamin Nanoparticle Release Systems for Cancer Cotherapy
Mol Pharm. 17(7):2612-2627 (2020). doi: 10.1021/acs.molpharmaceut.0c00308. (2020)
Application of Mechanical Forces on Drosophila Embryos by Manipulation of Microinjected Magnetic Particles
Bio-protocol 10(9), (2020) DOI: 10.21769/BioProtoc.3608 (2020)
Prediction of Antimalarial Drug-Decorated Nanoparticle Delivery Systems with Random Forest Models
Biology (Basel). 9(8):E198. (2020) doi: 10.3390/biology9080198. (2020)
The Golgi as an Assembly Line to the Autophagosome
Trends Biochem Sci. 45(6):484-496. (2020) doi: 10.1016/j.tibs.2020.03.010 (2020)
Characterization of monolayers and liposomes that mimic lipid composition of HeLa cells
Colloids Surf B Biointerfaces. 196:111288. (2020) doi: 10.1016/j.colsurfb.2020.111288 (2020)
Microfluidic chip with pillar arrays for controlled production and observation of lipid membrane nanotubes
Lab Chip. 20(15):2748-2755. (2020) doi: 10.1039/d0lc00451k (2020)
PTEN Activity Defines an Axis for Plasticity at Cortico-Amygdala Synapses and Influences Social Behavior
Cereb Cortex. 30(2):505-524. (2020) doi: 10.1093/cercor/bhz103. Corrigendum to: -PTEN activity defines an axis for plasticity at cortico-amygdala synapses and influences social behavior. Sánchez-Puelles C, Calleja-Felipe M, Ouro A, Bougamra G, Arroyo A, Diez I, Erramuzpe A, Cortés J, Martínez-Hernández J, Luján R, Navarrete M, Venero C, Chan A, Morales M, Esteban JA, Knafo S. Cereb Cortex. 30(2):849. (2020) doi: 10.1093/cercor/bhz232. (2020)
Therapeutic Pretargeting with Gold Nanoparticles as Drug Candidates for Boron Neutron Capture Therapy
Part Part Syst Char. 2000200 (2020) doi: 10.1002/ppsc.202000200 (2020)
The Six Isomers of the Cyclohexanol Dimer: A Delicate Test for Dispersion Models
Angew Chem Int Ed Engl. 59(33):14081-14085. (2020) doi: 10.1002/anie.202005063. (2020)
Substrate interaction inhibits ?-secretase production of amyloid-? peptides
Chem Commun (Camb). 56(17):2578-2581. (2020) doi: 10.1039/c9cc09170j. (2020)
Liver osteopontin is required to prevent the progression of age-related nonalcoholic fatty liver disease
Aging Cell. 19(8):e13183. (2020) doi: 10.1111/acel.13183 (2020)
Millimeter wave free-jet spectrum of acrolein and several isotopologues
Canadian Journal of Physics. 98(6) 555-559 (2020). doi: 10.1139/cjp-2019-0528. (2020)
PTML Multi-Label Algorithms: Models, Software, and Applications
Curr Top Med Chem. 20(25):2326-2337. (2020) doi: 10.2174/1568026620666200916122616. (2020)
Reconstitution and real-time quantification of membrane remodeling by single proteins and protein complexes
Nat Protoc. 15(8):2443-2469. (2020) doi: 10.1038/s41596-020-0337-1. (2020)
Extraction and Refolding Determinants of Chaperone-Driven Aggregated Protein Reactivation
J Mol Biol. 432(10):3239-3250. (2020) doi: 10.1016/j.jmb.2020.03.002. (2020)
Preformulation Studies of a Stable PTEN-PDZ Lipopeptide Able to Cross an In Vitro Blood-Brain-Barrier Model as a Potential Therapy for Alzheimer's Disease
Pharm Res, 37(10):183. (2020) doi: 10.1007/s11095-020-02915-8. (2020)
Toward Diffusion Measurements of Colloidal Nanoparticles in Biological Environments by Nuclear Magnetic Resonance
Small :e2001160. (2020) doi: 10.1002/smll.202001160. (2020)
Membrane fluidity adjusts the insertion of the transacylase PlsX to regulate phospholipid biosynthesis in Gram-positive bacteria
J Biol Chem. 295(7):2136-2147. (2020) doi: 10.1074/jbc.RA119.011122. (2020)